Browsing Experimentally Confirmed database

Result: Your query found 23 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
ceuE
  • BacMet ID: BAC0062
  • Code for: Membrane Transporter
  • Family: ABC superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Psudomonas aeruginosa
  • Location: Plasmid pUM505 (pseudomonas aeruginosa), Plasmid pB4 (uncultured bacterium), Plasmid pMOL28 (Ralstonia metallidurans (strain CH34/ATCC 43123/DSM2839))
  • Compound: Chromium (Cr)
  • Description: Periplasmic iron-binding protein Iron(III) ABC transporter CeuE; Encodes for membrane proteins; This protein reduces chromate (CrO4) accumulation and is essential for chromate resistance.
  • Length (amino acid): 313
  • Reference: Cervantes et al. 1990; Pubmed- 2152903, Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrA
  • BacMet ID: BAC0063
  • Code for: Efflux
  • Family: Chromate ion transporter (CHR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Psudomonas aeruginosa
  • Location: Plasmid pUM505 (pseudomonas aeruginosa)
  • Compound: Chromium (Cr)
  • Description: Chromate (CrO4) transport protein ChrA; Responsible for the inducibility of the resistance
  • Length (amino acid): 416
  • Reference: Cervantes et al. 1990; Pubmed- 2152903

    		• Similar resistance genes in 'BacMet Predicted database'
    chrA
  • BacMet ID: BAC0026
  • Code for: Efflux
  • Family: Chromate Ion Transporter (CHR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ochrobactrum tritici
  • Location: Chromosome (transposon TnOtChr)
  • Compound: Chromium (Cr)
  • Description: Part of chrBACF operon from the transposable element TnOtChr. It pumps chromate out of the cell.
  • Length (amino acid): 458
  • Reference: Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrA1
  • BacMet ID: BAC0548
  • Code for: Efflux
  • Family: Chromate ion transporter (CHR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ralstonia metallidurans (strain CH34/ATCC 43123/DSM2839)
  • Location: Plasmid pMOL28 (Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)), Plasmid pB4 (uncultured bacterium)
  • Compound: Chromium (Cr)
  • Description: This protein reduces chromate accumulation and is essential for chromate resistance.
  • Length (amino acid): 401
  • Reference: Juhnke et al. 2002; Pubmed- 12471500, Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrB
  • BacMet ID: BAC0027
  • Code for: Regulator
  • Family: Contains 1 Chromate resistance exported protein domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ochrobactrum tritici
  • Location: Chromosome (transposon TnOtChr)
  • Compound: Chromium (Cr), Methyl Viologen [class: Paraquat], Menadione [class: Naphthoquinone]
  • Description: Part of chrBACF operon from the transposable element TnOtChr. Has a regulatory role for expression of the ChrA transporter.
  • Length (amino acid): 312
  • Reference: Branco et al. 2013; Pubmed- 24223748, Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrB1
  • BacMet ID: BAC0064
  • Code for: Regulator
  • Family: Chromate ion transporter (CHR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ralstonia metallidurans (strain CH34/ATCC 43123/DSM2839)
  • Location: Plasmid pMOL28 (Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)), Plasmid pB4 (uncultured bacterium)
  • Compound: Chromium (Cr)
  • Description: Together with ChrA, this protein reduces chromate accumulation and is essential for chromate (CrO4) resistance, possibly as a regulatory protein.
  • Length (amino acid): 324
  • Reference: Juhnke et al. 2002; Pubmed- 12471500, Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrC
  • BacMet ID: BAC0547
  • Code for: Enzyme
  • Family: Iron/manganese superoxide dismutase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ralstonia metallidurans (strain CH34/ATCC 43123/DSM2839)
  • Location: Plasmid pMOL28 (Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)), Plasmid pB4 (uncultured bacterium)
  • Compound: Chromium (Cr)
  • Description: Fe-dependent Superoxide dismutase. This protein is not essential for chromate resistance, however it may contribute to resistance under certain environmental conditions. Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  • Length (amino acid): 197
  • Reference: Juhnke et al. 2002; Pubmed- 12471500

    		• Similar resistance genes in 'BacMet Predicted database'
    chrC
  • BacMet ID: BAC0028
  • Code for: Enzyme
  • Family: Iron/manganese superoxide dismutase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ochrobactrum tritici
  • Location: Chromosome (transposon TnOtChr)
  • Compound: Chromium (Cr), Methyl Viologen [class: Paraquat], Menadione [class: Naphthoquinone]
  • Description: Part of chrBACF operon from the transposable element TnOtChr. ChrC encodes a superoxide dismutase.
  • Length (amino acid): 202
  • Reference: Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrE
  • BacMet ID: BAC0065
  • Code for: Enzyme
  • Family: Rhodanese family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ralstonia metallidurans (strain CH34/ATCC 43123/DSM2839)
  • Location: Plasmid pMOL28 (Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)), Plasmid pB4 (uncultured bacterium)
  • Compound: Chromium (Cr)
  • Description: ChrE, involved in the processing of chromium-glutathione-complexes
  • Length (amino acid): 113
  • Reference: Juhnke et al. 2002; Pubmed- 12471500, Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrF
  • BacMet ID: BAC0066
  • Code for: Regulator
  • Family: Chrome_Resist family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ralstonia metallidurans (strain CH34/ATCC 43123/DSM2839)
  • Location: Plasmid pMOL28 (Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)), Plasmid pB4 (uncultured bacterium)
  • Compound: Chromium (Cr)
  • Description: ChrF, regulatory protein, involved in Chromate (CrO4) resistance
  • Length (amino acid): 140
  • Reference: Juhnke et al. 2002; Pubmed- 12471500

    		• Similar resistance genes in 'BacMet Predicted database'
    chrF
  • BacMet ID: BAC0029
  • Code for: Unknown
  • Family: Contains 1 Chromate resistance exported protein domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ochrobactrum tritici
  • Location: Chromosome (transposon TnOtChr)
  • Compound: Chromium (Cr), Methyl Viologen [class: Paraquat], Menadione [class: Naphthoquinone]
  • Description: Part of chrBACF operon from the transposable element TnOtChr.
  • Length (amino acid): 150
  • Reference: Branco et al. 2008; Pubmed- 18776016

    		• Similar resistance genes in 'BacMet Predicted database'
    chrI
  • BacMet ID: BAC0361
  • Code for: Regulator
  • Family: Unknown
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Ralstonia metallidurans (strain CH34/ATCC 43123/DSM2839)
  • Location: Plasmid pMOL28 (Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)), Plasmid pB4 (uncultured bacterium)
  • Compound: Chromium (Cr)
  • Description: ChrI, regulatory protein, involved in Chromate resistance.
  • Length (amino acid): 164
  • Reference: Juhnke et al. 2002; Pubmed- 12471500

    		• Similar resistance genes in 'BacMet Predicted database'
    chrR
  • BacMet ID: BAC0538
  • Code for: Enzyme
  • Family: NADH_dh2 family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas putida
  • Location: Chromosome
  • Compound: Chromium (Cr), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides], 2,6-dichloroindophenol [class: Phenolic Compounds]
  • Description: A soluble quinone reductase of Pseudomonas putida that defends against H2O2. ChrR is a dimeric flavin mononucleotide-binding flavoprotein that is able to catalyze a full reduction of Cr(VI) to Cr(III). ChrR may also contribute to the survival of P. putida in the environment by preventing redox cycling of soluble quinones. Confers resistance to Pottasium Ferricyanide (Fe++ salt) as well.
  • Length (amino acid): 186
  • Reference: Gonzalez et al. 2005; Pubmed- 15840577, Ackerley et al. 2004; Pubmed- 14766567, Park et al. 2000; Pubmed- 10788340

    		• Similar resistance genes in 'BacMet Predicted database'
    chrR
  • BacMet ID: BAC0539
  • Code for: Enzyme
  • Family: NADH_dh2 family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas sp. (strain G-1)
  • Location: Chromosome
  • Compound: Chromium (Cr)
  • Description: Cr(VI) reductase. Absent in P. putida.
  • Length (amino acid): 243
  • Reference: Suzuki et al. Pubmed- 1992; Pubmed- 1322884

    		• Similar resistance genes in 'BacMet Predicted database'
    mdrL/yfmO
  • BacMet ID: BAC0209
  • Code for: Efflux
  • Family: MFS superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Listeria monocytogenes
  • Location: Chromosome
  • Compound: Zinc (Zn), Cobalt (Cobalt), Chromium (Cr), Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Multidrug resistance transporter mdrL/YfmO. It can confer resistance to antibiotics such as erythromycin, josamycin, clindamycin etc.
  • Length (amino acid): 397
  • Reference: Mata et al. 2000; Pubmed- 10856655

    		• Similar resistance genes in 'BacMet Predicted database'
    nfsA
  • BacMet ID: BAC0540
  • Code for: Enzyme
  • Family: Flavin oxidoreductase frp family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli K12
  • Location: Chromosome
  • Compound: Chromium (Cr)
  • Description: A major oxygen-insensitive nitroreductase of Escherichia coli, is a flavoprotein that is able to reduce chromate to less soluble and less toxic Cr(III). Reduction of nitroaromatic compounds using NADH. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major component of the oxygen-insensitive nitroreductase activity in E.coli.
  • Length (amino acid): 240
  • Reference: Ackerley et al. 2004; Pubmed- 15250887

    		• Similar resistance genes in 'BacMet Predicted database'
    oscA
  • BacMet ID: BAC0358
  • Code for: Binding protein
  • Family: Unknown
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas corrugata 28
  • Location: Chromosome
  • Compound: Chromium (Cr), Dodine [class: Acetate]
  • Description: oscA gene involved in the sulphur starvation response and in Cr(VI) resistance in Pseudomonas corrugata 28. oscA is located upstream of a gene cluster that encodes the components of the sulphate ABC transporter, and it forms a single transcriptional unit with sbp, which encodes the periplasmic sulphate-binding protein. It has been shown that oscA is essential for the utilization of various organosulphur compounds and that it induces upregulation of the cysTWA operon under conditions of chromate exposure. oscA may also have a regulatory role in the sulphur starvation response, but the exact mechanism through which it acts is not well understood.
  • Length (amino acid): 60
  • Reference: Viti et al. 2009; Pubmed- 19118350

    		• Similar resistance genes in 'BacMet Predicted database'
    recG
  • BacMet ID: BAC0356
  • Code for: Enzyme
  • Family: Contains 1 DEAD/DEAH box helicase domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas aeruginosa PAO1
  • Location: Chromosome
  • Compound: Chromium (Cr), Tellurium (Te), Selenium (Se)
  • Description: ATP-dependent DNA helicase RecG. It is involved in repairing DNA damage caused by chromate or its derivatives. Can confer resistant to tellurite, selenite but not arsenite, paraquat or hydrogen peroxide.
  • Length (amino acid): 691
  • Reference: Miranda et al. 2005; Pubmed- 16105671, Decorosi et al. 2009; Pubmed- 19768364

    		• Similar resistance genes in 'BacMet Predicted database'
    recG
  • BacMet ID: BAC0357
  • Code for: Enzyme
  • Family: Contains 1 DEAD/DEAH box helicase domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas corrugata 28
  • Location: Chromosome
  • Compound: Chromium (Cr)
  • Description: fragment of the recG helicase.
  • Length (amino acid): 156
  • Reference: Decorosi et al. 2009; Pubmed- 19768364

    		• Similar resistance genes in 'BacMet Predicted database'
    ruvB
  • BacMet ID: BAC0355
  • Code for: Enzyme
  • Family: RuvB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas aeruginosa PAO1
  • Location: Chromosome
  • Compound: Chromium (Cr), Tellurium (Te), Selenium (Se)
  • Description: ATP-dependent DNA helicase RuvB. It is involved in repairing DNA damage caused by chromate or its derivatives. Can confer resistant to tellurite, selenite but not arsenite, paraquat or hydrogen peroxide.
  • Length (amino acid): 352
  • Reference: Miranda et al. 2005; Pubmed- 16105671, Decorosi et al. 2009; Pubmed- 19768364

    		• Similar resistance genes in 'BacMet Predicted database'
    ruvB
  • BacMet ID: BAC0293
  • Code for: Enzyme
  • Family: Malic enzymes family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Pseudomonas corrugata 28
  • Location: Chromosome
  • Compound: Chromium (Cr), Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Dodine [class: Acetate], 2-nitroimidazole [class: imidazole]
  • Description: It is a fragment of ruvB gene product. It is a oxidoreductase from malic enzyme family.
  • Length (amino acid): 379
  • Reference: Decorosi et al. 2009; Pubmed- 19768364

    		• Similar resistance genes in 'BacMet Predicted database'
    srpC
  • BacMet ID: BAC0152
  • Code for: Efflux
  • Family: Chromate Ion Transporter (CHR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Synechococcus elongatus strain PCC 7942 (Anacystis nidulans R2)
  • Location: Plasmid pANL
  • Compound: Chromium (Cr)
  • Description: A homologue of chrA. SrpC is not a sulfate transporter. Functions as a transporter that extrudes chromate ions from cytoplasm under sulfur-deficient conditions.
  • Length (amino acid): 393
  • Reference: Aguilar-Barajas et al. 2012; Pubmed- 22805806

    		• Similar resistance genes in 'BacMet Predicted database'
    yieF
  • BacMet ID: BAC0541
  • Code for: Enzyme
  • Family: SsuE family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli K12
  • Location: Chromosome
  • Compound: Chromium (Cr), Vanadium (V), Molybdenum (Mo), Methylene Blue [class: Thiazinium]
  • Description: A chromate reductase. Reduces chromate (Cr(VI)) to Cr(III)
  • Length (amino acid): 188
  • Reference: Ackerley et al. 2004; Pubmed- 14766567

    		• Similar resistance genes in 'BacMet Predicted database'
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